Projects per year
Personal profile
Biography
Since finishing her PhD, Dr. Sweta Rani is actively involved in research, identifying biomarkers in disease and biomarkers for drug response. Her research outputs include 21 peer reviewed research articles and 4 review articles in high impact factor journals. She also published 7 book chapters and edited 2 books and her h-index is 20 with more than 3274 citations. She was awarded - Best Business Opportunity award, (Ignite Technology Transfer Office Eco-System); Early Career Award - Barcroft medal, (Royal Academy Of Medicine in Ireland and Biomedical Sciences); Irish Association for Cancer Research Award for Travel - Annual IACR conference; and Grant for travel- EMBL Advanced Training Centre Corporate Partnership Programme and EMBO Travel Grants, Postdoctoral education grant (Fannin grant), Irish Endocrine Society (summer student research grant) and won Illumina MiSeq at TrinSeq Competition.
As a research fellow in Trinity College Dublin, Ireland, she worked with diverse cancer type including HER2+ breast cancer, triple negative breast cancer, lung cancer and prostate cancer. Her work aimed to identify circulating biomarkers using microarray and molecular mechanism of acquired resistance to the drugs. Extensive molecular biology technique to alter the gene expression (transient, permanent knock-down and over-expression) was used, to understand the molecular mechanism of drug resistance.
Recently, her main focus is disease of the eye including corneal burn model, age-related macular degeneration (AMD) and dry eye.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Investigation of molecular and cellular events associated with beta cell function and elucidation of extracellular RNAs as potential biomarker for diabetes, Dublin City University
Award Date: 28 Mar 2009
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Collaborations and top research areas from the last five years
Projects
- 3 Active
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Continuous Monitoring of Acquired Resistance to Targeted Therapy using Circulating Small RNA Sequences
Rani, S. & Vo, T. H.
01/09/2022 → 06/09/2026
Project: National
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Investigating the Role of Glatiramer Acetate in Modulating Immune Effector Cells in Wet Age-Related Macular Degeneration.
Rani, S. & Kuruppilakath Manikandan, S.
11/11/2019 → 04/03/2024
Project: National
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Exosomal MicroRNA Discovery in Age-Related Macular Degeneration
Elshelmani, H. & Rani, S., 2023, Methods in Molecular Biology. Humana Press Inc., p. 137-158 22 p. (Methods in Molecular Biology; vol. 2595).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
2 Citations (Scopus) -
Preface
Rani, S., 2023, In: Methods in Molecular Biology. 2595, p. vResearch output: Contribution to journal › Editorial
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miRNA Biogenesis and Regulation of Diseases: An Updated Overview
Vishnoi, A. & Rani, S., 29 Nov 2022, Methods in Molecular Biology. Humana Press Inc., Vol. 2595. p. 1-12 12 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
13 Citations (Scopus) -
Serum MicroRNAs Profiling in Age-Related Macular Degeneration
Elshelmani, H., Keegan, D. & Rani, S., 29 Nov 2022, Methods in Molecular Biology. Humana Press Inc., Vol. 2595. p. 123-135 13 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
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Chitosan-coated plga nanoparticles encapsulating triamcinolone acetonide as a potential candidate for sustained ocular drug delivery
Dandamudi, M., McLoughlin, P., Behl, G., Rani, S., Coffey, L., Chauhan, A., Kent, D. & Fitzhenry, L., Oct 2021, In: Pharmaceutics. 13, 10, 1590.Research output: Contribution to journal › Article › peer-review
Open Access32 Citations (Scopus)