A Process for Producing Amides and Acids using a Nitrile-Metabolising Enzyme: SS-17

Lee V. Coffey (Inventor), Catherine O'Reilly (Inventor), Claire Lennon (Inventor), Tracey Coady (Inventor), Erica Owens (Inventor), Panagiotis Manesiotis (Inventor), Karen Tambling (Inventor)

Research output: Patent

1 Downloads (Pure)

Abstract

The present invention relates to an isolated Nitrile-Metabolising Pantoea strain deposited under NCIMB 41854 and to amide or acid-producing mutants and variants thereof. Also provided is an isolated nucleotide sequence or polypeptide obtainable from the Nitrile-Metabolising Pantoea strain of the invention wherein the isolated nucleotide sequence or polypeptide encodes or is a nitrilase. The strain, isolated nucleotide sequence or polypeptide of the invention may be used in a process for producing a carboxylic acid by metabolising nitriles such as 3-hydroxyglutaronitrile, 3-hydroxy-butyronitrile and 3-hydroxy-phenylpropionitrile to form corresponding carboxylic acids.
Original languageEnglish (Ireland)
Patent number1111639.9
Filing date07/07/2011
Publication statusPublished - 07 Jul 2011

Fingerprint

Dive into the research topics of 'A Process for Producing Amides and Acids using a Nitrile-Metabolising Enzyme: SS-17'. Together they form a unique fingerprint.

Cite this