Análise sobre o Impacto de Topologias de Astrócitos em um Sistema de Comunicação Molecular baseado em Sinalização de Ca2+

In the human body there is a wide variety of molec- ular communications systems. A particular type of molecular communication is based on calcium (Ca2+) signaling, which consists of a communication process that diffuses and propagates ions between the cells of a tissue. Ca2+ signaling occurs in different cells, among them the astrocyte, which is present in the central nervous system. Thus, this molecular communication system consists of astrocytes that are connected to each other by means of gap junctions, and can be modeled as a network that has different coupling topologies. Therefore, in the present work, an analysis of the gain of the communication channel was performed for three network topologies: Regular Degree, Link Radius and Shortcut. The shortcut topology presented a gain six times greater, compared to the other topologies. This analysis of the behavior of the communication provides useful information for the design of nanoredes that are able to act at the molecular level, introducing in them the performance of intercellular communication more adequate.