Caffeoylquinic acids from leaves of Etlingera species (Zingiberaceae)

E. W.C. Chan, Y. Y. Lim, S. K. Ling, S. P. Tan, K. K. Lim, M. G.H. Khoo

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50 Citations (Scopus)


3-O-caffeoylquinic acid, 5-O-caffeoylquinic acid (chlorogenic acid), and 5-O-caffeoylquinic acid methyl ester, as elucidated by 1H and 13C NMR, were isolated from leaves of Etlingera elatior. This is the first report of caffeoylquinic acids (CQA) including chlorogenic acid (CGA) in Zingiberaceae. Leaves of Etlingera species were rich in total phenols and CQA, and non-cytotoxic to normal human liver and African green monkey kidney cells. Content of CQA of E. elatior, Etlingera fulgens, and Etlingera rubrostriata leaves was significantly higher than leaves of Ipomoea batatas, and comparable to flowers of Lonicera japonica. CGA found only in leaves of E. elatior and E. fulgens was significantly higher in content than flowers of L. japonica, the commercial source.

Original languageEnglish
Pages (from-to)1026-1030
Number of pages5
JournalLWT - Food Science and Technology
Issue number5
Publication statusPublished - Jun 2009
Externally publishedYes


  • Chlorogenic acid
  • Cytotoxicity
  • Etlingera
  • Ipomoea batatas
  • Lonicera japonica
  • Total phenols


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