Characterization of enterocin- and salivaricin-producing lactic acid bacteria from the mammalian gastrointestinal tract: RESEARCH LETTER

Eileen F. O'shea, Gillian E. Gardiner, Paula M. O'connor, Susan Mills, R. Paul Ross, Colin Hill

Research output: Contribution to journalArticlepeer-review

43 Citations (Scopus)

Abstract

Bacteriocin production may be a factor contributing to bacterial dominance within complex microbial populations and may therefore be a common trait within the gut microbiota. However, of 278 antimicrobial-producing culturable lactic acid bacteria (LAB) isolated from a range of mammalian intestinal sources in this study, characterization revealed just 23 distinct strains producing bacteriocin-like inhibitory substances and one Streptococcus hyointestinalis strain producing a potentially novel protease-insensitive antimicrobial. Three class II bacteriocins previously isolated from intestinal-derived LAB were identified as enterocin A and two salivaricin P-like bacteriocins. Moreover, this is the first report of intestinal-derived Streptococcus salivarius producing variants of the lantibiotic salivaricin A.

Original languageEnglish
Pages (from-to)24-34
Number of pages11
JournalFEMS Microbiology Letters
Volume291
Issue number1
DOIs
Publication statusPublished - Feb 2009
Externally publishedYes

Keywords

  • Bacteriocin
  • enterocin A
  • Gastrointestinal tract
  • Lactic acid bacteria
  • Salivaricin A
  • Salivaricin P

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