Development of contact lenses for ocular drug delivery

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

This study focussed on the development of a manufacturing and characterisation process for the production of contact lenses with controlled release properties. Three lens compositions with varying degrees of cross-linking (CL) density were studied, A (2.7% w/w), B (3.8% w/w) and C (7.8% w/w) The formulations were studied to determine the effect of CL density on the loading of Vitamin E. Vitamin E was loaded into the three polymer compositions with increased capacity observed with decreasing cross-link density, (1.8, 1.6 and 1.1 mg of Vitamin E loaded per lens for A, B and C, respectively). Critically Vitamin E was not released from the loaded lenses.

Original languageEnglish
Title of host publicationSociety of Plastics Engineers - EUROTECH 2013
PublisherSociety of Plastics Engineers
Pages285-289
Number of pages5
ISBN (Print)9781632665324
Publication statusPublished - 2013
EventEUROTECH 2013 - Lyon, France
Duration: 04 Jul 201305 Jul 2013

Publication series

NameSociety of Plastics Engineers - EUROTECH 2013

Conference

ConferenceEUROTECH 2013
Country/TerritoryFrance
CityLyon
Period04/07/201305/07/2013

Keywords

  • Contact lenses
  • DSC and texture analysis
  • Drug delivery
  • Hydrogel

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