Macular pigment and its contribution to vision

Ekaterina Loskutova, John Nolan, Alan Howard, Stephen Beatty

Research output: Contribution to journalArticlepeer-review

43 Citations (Scopus)

Abstract

Three dietary carotenoids, lutein (L), zeaxanthin (Z) and meso-zeaxanthin (MZ) accumulate at the central retina (macula), where they are collectively referred to as macular pigment (MP). MP's pre-receptoral absorption of blue light and consequential attenuation of the effects of chromatic aberration and light scatter are important for optimal visual function. Furthermore, antioxidant activity of MP's constituent carotenoids and the same blue light-filtering properties underlie the rationale for its putative protective role for age-related macular degeneration (AMD). Supplementation with L, Z and MZ augments MP and enhances visual performance in diseased and non-diseased eyes, and may reduce risk of AMD development and/or progression.

Original languageEnglish
Pages (from-to)1962-1969
Number of pages8
JournalNutrients
Volume5
Issue number6
DOIs
Publication statusPublished - 29 May 2013

Keywords

  • Lutein
  • Macular pigment
  • Meso-zeaxanthin
  • Visual performance
  • Zeaxanthin

Fingerprint

Dive into the research topics of 'Macular pigment and its contribution to vision'. Together they form a unique fingerprint.

Cite this