Melt Extrusion of High-Dose Co-Amorphous Drug-Drug Combinations: Theme: Formulation and Manufacturing of Solid Dosage Forms Guest Editors: Tony Zhou and Tonglei Li

Lærke Arnfast, Md Kamruzzaman, Korbinian Löbmann, Johanna Aho, Stefania Baldursdottir, Thomas Rades, Jukka Rantanen

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)2689-2697
JournalPharmaceutical Research
Publication statusPublished - 19 Sep 2017
Externally publishedYes


  • Hot melt extrusion
  • Co-amorphous
  • Processability
  • drug combinations
  • Rheology
  • Solid state characterization
  • DSC
  • TGA
  • Dynamic Vapor Sorption
  • stability
  • Storage conditions
  • Glass transition temperature
  • XRPD
  • melt viscosity
  • Indomethacin
  • Cimetidine
  • Polyethylene oxide
  • amorphous materials

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