Polyamide/silver antimicrobials: Effect of filler types on the silver ion release

Radhesh Kumar, Steve Howdle, Helmut Münstedt

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    164 Citations (Scopus)


    Abstract: The efficiency of various silver-based antimicrobial fillers (elementary silver and silver substituted materials) in polyamide (PA) toward their silver ion (Ag�) release characteristics in an aqueous medium was investigated and discussed. Anode stripping voltammetry (ASV) was used for the quantitative estimation of Ag� release from these composites. The biocidal (Ag�) release from the composites was found to be dependent on the time of soaking in water and the nature of the filler. The long-term Ag� release capability of the elementary silver-based PA/Ag composite is promising compared with the commercial counterparts. The silver ion release potential of polyamide composites where the silver filling was performed by using supercritical carbon dioxide (scCO2) is also discussed. The composites release Ag� at a concentration level capable of rendering antimicrobial efficacy and proved to be active against the microbes. A good agreement exists between the Ag� release experiments and antimicrobial test results. The observed results on the influence of the nature of the filler and crystallinity on the biocidal release and the varying long-term release properties could be helpful in the design of industrially relevant biomaterials. © 2005 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater 75B: 311–319, 2005
    Original languageEnglish
    Pages (from-to)311-319
    JournalJournal of Biomedical Materials Research Part B: Applied Biomaterials
    Issue number2
    Publication statusPublished - 2005


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