Salivaricin p, one of a family of two-component antilisterial bacteriocins produced by intestinal isolates of Lactobacillus salivarius

Eoin Barrett, Maria Hayes, Paula O'Connor, Gillian Gardiner, Gerald F. Fitzgerald, Catherine Stanton, R. Paul Ross, Colin Hill

Research output: Contribution to journalArticlepeer-review

57 Citations (Scopus)

Abstract

Lactobacillus salivarius DPC6005, a porcine intestinal isolate, produces a two-component bacteriocin, salivaricin P, with homology to ABP-118 produced by a human probiotic L. salivarius strain. Indeed, molecular characterization revealed that while the peptides Sln1 and ABP-118α are identical, their companion peptides (Sln2 and ABP-118β, respectively) differ by two amino acids. This observation suggests that two-component bacteriocins may be a common feature of intestinal L. salivarius strains.

Original languageEnglish
Pages (from-to)3719-3723
Number of pages5
JournalApplied and Environmental Microbiology
Volume73
Issue number11
DOIs
Publication statusPublished - Jun 2007
Externally publishedYes

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