Synthetic protocols for nano sensor transmitting platforms using enzyme and DNA based computing

Frank Walsh, Sasitharan Balasubramaniam, Dmitri Botvich, William Donnelly

Research output: Contribution to journalArticlepeer-review

16 Citations (Scopus)


The ability to create communication networks of biological nanoscale devices has the potential to open up new opportunities and applications, particularly in areas such as health care and information processing. Inspired by recent developments in molecular communication and biomolecular computing, we present in this paper a biological cell based molecular communication transmitting platform using synthetic molecular computing techniques. We investigated two protocol solutions which include DNA based computing coupled with viral particles and enzyme based computing coupled with calcium signaling. Each of these solutions is designed for different applications and environments. For each of these approaches we demonstrate how elements from various layers in the communication stack are developed using the molecular computing mechanisms. Simulation results are also presented to illustrate the functionality and performance of each solution.

Original languageEnglish
Pages (from-to)50-62
Number of pages13
JournalNano Communication Networks
Issue number1
Publication statusPublished - Mar 2010


  • DNA computing
  • Enzyme computing
  • Nano communication protocols


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